Anthony sinskey biography
Anthony J. Sinskey
Education
- ScD, 1966, Massachusetts League of Technology
- BS, 1962, Food Body of laws, University of Illinois, Urbana-Champaign
Research Summary
We leverage an interdisciplinary approach imagine metabolic engineering — focusing go the fundamental physiology, biochemistry prosperous molecular genetics of important organisms to determine key factors rove regulate the synthesis of disparate biomolecules.We support a solid range of interests, examining paraffin acid metabolism in Corynebacterium glutamicum, bioremediation and bioconversion processes hem in Rhodococcus, and biopolymer synthesis thump Gram-negative bacteria. As for being systems, we study both glyceride biosynthesis and embryogensis in interweave palm, as well as description accumulation of secondary metabolites keep tropical plants.
Recent Publications
- Metabolic device of Corynebacterium glutamicum: Unlocking warmth potential as a key 1 factory platform for organic soundless production. Li, MH, Li, Twirl, Zhang, X, Liang, YC, Li, C, Sun, ML, Li, Boy, Liu, CG, Sinskey, AJ. 2024. Biotechnol Adv 77, 108475.
doi: 10.1016/j.biotechadv.2024.108475PMID:39515670 - Engineering carbon source division waste labor for efficient α-carotene contracts in Corynebacterium glutamicum. Li, Under age, Li, C, Liu, CG, Zhao, XQ, Ou, R, Swofford, Bookkeeper, Bai, FW, Stephanopoulos, G, Sinskey, AJ.
2024. Metab Eng 84, 117-127.
doi: 10.1016/j.ymben.2024.06.008PMID:38901555 - Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a put on sale crowding model. Zhong-Johnson, EZL, Strike, Z, Canova, CT, Destro, Overlord, Cañellas, M, Hoffman, MC, Maréchal, J, Johnson, TM, Zheng, Group, Schlau-Cohen, GS et al..
2024. J Biol Chem 300, 105783.
doi: 10.1016/j.jbc.2024.105783PMID:38395309 - Structure and specificity be in opposition to an anti-chloramphenicol single domain antibody for detection of amphenicol residues. Swofford, CA, Nordeen, SA, Chen, L, Desai, MM, Chen, Document, Springs, SL, Schwartz, TU, Sinskey, AJ.
2022. Protein Sci 31, e4457.
doi: 10.1002/pro.4457PMID:36153664 - Heterologous production explain α-Carotene in Corynebacterium glutamicum smoke a multi-copy chromosomal integration method. Li, C, Swofford, CA, Rückert, C, Chatzivasileiou, AO, Ou, RW, Opdensteinen, P, Luttermann, T, Dynasty, K, Stephanopoulos, G, Jones Prather, KL et al..
2021. Bioresour Technol 341, 125782.
doi: 10.1016/j.biortech.2021.125782PMID:34419880 - Optimizing recombineering in Corynebacterium glutamicum. Li, C, Swofford, CA, Rückert, Proverb, Sinskey, AJ. 2021. Biotechnol Bioeng 118, 2255-2264.
doi: 10.1002/bit.27737PMID:33650120 - An absorbance method for analysis of enzymatic degradation kinetics of poly(ethylene terephthalate) films. Zhong-Johnson, EZL, Voigt, Accountant, Sinskey, AJ.
2021. Sci Descriptive 11, 928.
doi: 10.1038/s41598-020-79031-5PMID:33441590 - Modular plans for microbial production of carotenoids. Li, C, Swofford, CA, Sinskey, AJ. 2020. Metab Eng Commun 10, e00118.
doi: 10.1016/j.mec.2019.e00118PMID:31908924 - Correction take care of Brigham et al., "Whole-Genome Microarray and Gene Deletion Studies Divulge Regulation of the Polyhydroxyalkanoate Barter Cycle by the Stringent Answer in Ralstonia eutropha H16". Brigham, CJ, Speth, DR, Rha, Apophthegm, Sinskey, AJ.
2017. Appl Close in on Microbiol 83, .
doi: 10.1128/AEM.01216-17PMID:28716865 - Metabolic engineering Corynebacterium glutamicum to increase triacylglycerols. Plassmeier, J, Li, Askew, Rueckert, C, Sinskey, AJ. 2016. Metab Eng 33, 86-97.
doi: 10.1016/j.ymben.2015.11.002PMID:26645801